Long ago, when EFI was new, injectors tended to accumulate 'varnish', which interfered with atomization, and, e.g. made a FI car run like a carbureted car with plugged transition jets.
Varnish accumulates in typical commuter drive cycles, which were not simulated during EFI development, where the engines were run continuously, not parked and hot-soaked. Recent injectors are varnish- tolerant, and the fuel has changed some, too.g
My 85 Camaro V6 ran like it needed a valve job when the injectors got varnished up.
The only thing that was effective against the varnish was Marvel Mystery Oil, added to the fuel at 4 fl. oz. per 12 gallon fillup. It usually made an amazing and amazingly rapid change in the car's drivability, within ten miles or less.
In the five Camaros I've owned since then, MMO made a less spectacular difference, and wasn't needed on a regular basis. But if you have a EFI car or a carbureted car that's feeling a little funky, MMO is still the cheapest thing to try first.